LITERATURE STUDY OF L-CARNITINE PREPARATION  METHODS FOR 1000 TONS OF ANNUAL PRODUCTION

Annida Khoirun Nisa  Purwadini; Cucuk Evi  Lusiani

doi:10.33795/distilat.v8i2.386

Authors

Annida Khoirun Nisa Purwadini Jurusan Teknik Kimia, Politeknik Negeri Malang, Jl. Soekarno Hatta No. 9, Malang 65141, Indonesia
Cucuk Evi Lusiani Jurusan Teknik Kimia, Politeknik Negeri Malang, Jl. Soekarno Hatta No. 9, Malang 65141, Indonesia

DOI:

https://doi.org/10.33795/distilat.v8i2.386

Keywords:

Annual Production, L-carnitine, Selection Process

Abstract

L-carnitine is a gamma-hydroxy amino acid and also known as vitamin Bγ. L-carnitine has many benefits as well as uses. Supplements with L-carnitine content are much needed in the field of health. L-carnitine is obtained using a variety of methods. They are the chemical optic resolution method, the biological method, and those that use chiral materials from natural sources. The purpose of this literature study is to determine the best method to be used in the design of the L-carnitine production plant with a capacity of 1000 tons per year by comparing various existing methods from various aspects. Based on the results of the comparison, it was found that the production of L-carnitine from (S)-3-activated hydroxybutyrolactone is the best method to be used in the production of L-carnitine capacity of 1000 tons per year for 300 days. This method produces a lot-more L carnitine products at a lower cost than other methods that have a higher yield.

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